Coming full circle from the ban on sassafras based on allelopathic rodent responses (humans are not allelopathic as to sassafras, so why use rodents for us?), it now appears that medical benefits from sassafras could outweigh earlier imprudent restrictions on use of elements of sassafras. See http://psychcentral.com/news/2010/12/17/drug-%E2%80%98ecstasy%E2%80%99-may-help-individuals-with-schizophrenia-autism/21876.html/ Long used as a hospitality beverage -- loosening everyone up -- good uses were known and promulgated back in 1983, for example, see http://www.motherearthnews.com/organic-gardening/sassafras-uses-herbal-medicine-zmaz83jazshe.aspx/. Farther back, starting at least in 1603, hunting the sassafras to bring back the roots was profitable and healthful, see http://sites.google.com/site/atimelineofamerica/1603/ Sir Walter Raleigh had been given rights to develop the possibilties by Elizabeth I, see site. Alas, add, in 1997, the book Food Safety and Toxicity, edited by John DeVries, the unexamined claim of carcinogenic safrole and the use of mice to conclude that, at page 128.
Call for more testing, without rodents, please, Mr. DeVries.
Add to the list of conditions to be tested with sassafras: PTSD. Is the safrole in sassafras as dire as publicized? Not necessarily, see http://www.homebrewtalk.com/showthread.php?t=218174/ Is it more likely that the rampant natural availability of sassafras, read: not profit producing if you can raise it in your yard -- and the industries who like labs instead, are at work?
Any overload use can be addressed as we do with alcohol, sudafed, other matters where reasonable restrictions on purchases apply. PTSD: The Evil Hours, by David J. Morris, this review by Jen Percy, does not address use of sassafras, to my recollection. To be checked.
Wax poetic. Enjoy http://hellopoetry.com/words/19353/sassafras/poems/